Endocrine Abstracts

Introduction: Visceral adipose tissue (VAT) is closely related to metabolic derangement, such as dyslipidemia insulin resistance and type 2 diabetes. Also, there is an increase in deposition of visceral adipose tissue in hypogonadal subjects. The visceral adiposity index (VAI) is a sex-specific mathematical index, based on waist circumference (WC), body mass index (BMI), triglycerides (TG) and HDL cholesterol (HDL) levels, indirectly expressing visceral adipose function. We in...

The present study was performed to search whether SCAT increase in women with PCOS. Fifty-two women with PCOS patients and 53 matched healthy controls were participated in the study. Caliper device was used to measure skinfold thickness (SFT). Body fat distributions were determined by bioelectrical impedance analysis. SFT in all defined areas, total body and trunk fat free mass (FFM), and HOMA score were higher in women with PCOS, while adiponectin was significantly lower. SFT...

PCOS is characterized by insulin resistance. Inflammation has been anticipated to play role in the pathogenesis of both insulin resistance and atherosclerosis. Pentraxin 3 (PTX3) is an inflammatory mediator synthesized in a variety of cells and tissues. In the present study, serum PTX3 level and its relationship with insulin resistance were investigated in patients with PCOS. In total, 40 patients with PCOS and 40 age and body mass index (BMI) matched healthy controls were enr...

Objective: The relationship between metabolic syndrome (MS) and hypogonadism has always been investigated in study groups confounded with aging, obesity or chronic metabolic disorders. So far there has been no data about the presence of MS in young hypogonadal patients. Also there is controversial data about the metabolic effects of testosteron replacement therapy. We investigated the frequency of MS in treatment naïve, young men with congenital hypogonadal hypogonadism (...